The Relationship Between Leptin:Adiponectin Ratio and Carotid Intima-Media Thickness in Asymptomatic Females

To the Editor:A leptin-to-adiponectin ratio (L:A) is a new index to assess atherogenesis in diabetic patients.1 More recently, Norata et al2 have reported that L:A shows a powerful correlation to intima-media thickness (IMT) of the common carotid artery (CCA) in healthy males. This expands the possibilities of the applications of L:A in clinical practice on not only diabetics but also healthy subjects. However, to establish the applications of L:A, further studies on various healthy populations are needed, as the Norata study was for males only and on a wide range of age2 (we found that a clinical significance of L:A could be modified with age1). Thus, the present report adds to the results on an association of L:A with CCA-IMT in healthy females, with a restriction to …