Dual-Modality Monitoring of Targeted Intraarterial Delivery of Mesenchymal Stem Cells After Transient Ischemia | Zendy

Piotr Walczak | Zendy; Jian Zhang | Zendy; Assaf A. Gilad | Zendy; Dorota Kedziorek | Zendy; Jesús RuízCabello | Zendy; Randell G. Young | Zendy; Mark F. Pittenger | Zendy; Peter C.M. van Zijl | Zendy; Judy Huang | Zendy; Jeff W. M. Bulte | Zendy

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Dual-Modality Monitoring of Targeted Intraarterial Delivery of Mesenchymal Stem Cells After Transient Ischemia

Author(s) -

Piotr Walczak,

Jian Zhang,

Assaf A. Gilad,

Dorota Kedziorek,

Jesús RuízCabello,

Randell G. Young,

Mark F. Pittenger,

Peter C.M. van Zijl,

Judy Huang,

Jeff W. M. Bulte

Publication year - 2008

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.107.502047

Subject(s) - medicine , mesenchymal stem cell , ischemia , modality (human–computer interaction) , transient (computer programming) , stem cell , surgery , pathology , cardiology , microbiology and biotechnology , biology , human–computer interaction , computer science , operating system

In animal models of stroke, functional improvement has been obtained after stem cell transplantation. Successful therapy depends largely on achieving a robust and targeted cell engraftment, with intraarterial (IA) injection being a potentially attractive route of administration. We assessed the suitability of laser Doppler flow (LDF) signal measurements and magnetic resonance (MR) imaging for noninvasive dual monitoring of targeted IA cell delivery.

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