MMP-9–Positive Neutrophil Infiltration Is Associated to Blood–Brain Barrier Breakdown and Basal Lamina Type IV Collagen Degradation During Hemorrhagic Transformation After Human Ischemic Stroke | Zendy

Anna Rosell | Zendy; Eloy Cuadrado | Zendy; Arantxa OrtegaAznar | Zendy; Mar HernándezGuillamón | Zendy; Eng H. Lo | Zendy; Joan Montaner | Zendy

Open Access

MMP-9–Positive Neutrophil Infiltration Is Associated to Blood–Brain Barrier Breakdown and Basal Lamina Type IV Collagen Degradation During Hemorrhagic Transformation After Human Ischemic Stroke

Author(s) -

Anna Rosell,

Eloy Cuadrado,

Arantxa OrtegaAznar,

Mar HernándezGuillamón,

Eng H. Lo,

Joan Montaner

Publication year - 2008

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.107.500868

Subject(s) - medicine , basal lamina , blood–brain barrier , pathology , infiltration (hvac) , ischemic stroke , matrix metalloproteinase , stroke (engine) , ischemia , ultrastructure , central nervous system , physics , thermodynamics , mechanical engineering , engineering

An abnormal expression of some matrix metalloproteinases (MMPs) is related with hemorrhagic transformation events after stroke. Our aim was to investigate MMP-2 and MMP-9 in the ischemic brain and its relation with blood-brain barrier breakdown after hemorrhagic transformation in human stroke.

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