Progression of Symptomatic Intracranial Large Artery Atherosclerosis Is Associated With a Proinflammatory State and Impaired Fibrinolysis | Zendy

Juan F. Arenillas | Zendy; José ÁlvarezSabín | Zendy; Carlos A. Molina | Zendy; Pilar Chacón | Zendy; Israel FernándezCadenas | Zendy; Marc Ribó | Zendy; Pilar Delgado | Zendy; Marta Rubiera | Zendy; Anna Peñalba | Zendy; Àlex Rovira | Zendy; Joan Montaner | Zendy

Open Access

Progression of Symptomatic Intracranial Large Artery Atherosclerosis Is Associated With a Proinflammatory State and Impaired Fibrinolysis

Author(s) -

Juan F. Arenillas,

José ÁlvarezSabín,

Carlos A. Molina,

Pilar Chacón,

Israel FernándezCadenas,

Marc Ribó,

Pilar Delgado,

Marta Rubiera,

Anna Peñalba,

Àlex Rovira,

Joan Montaner

Publication year - 2008

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.107.498600

Subject(s) - medicine , fibrinolysis , proinflammatory cytokine , tissue plasminogen activator , plasminogen activator , plasminogen activator inhibitor 1 , c reactive protein , gastroenterology , inflammation , endocrinology

The molecular pathways involved in the progression of intracranial large artery atherosclerosis (ILA) are largely unknown. Our objective was to prospectively study the relationship between circulating levels of inflammatory markers and fibrinolysis inhibitors, and the risk of progression of symptomatic ILA.

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