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Misclassified Tissue Volumes in Alzheimer Disease Patients With White Matter Hyperintensities
Author(s) -
Naama LevyCooperman,
Joel Ramirez,
Nancy J. Lobaugh,
Sandra E. Black
Publication year - 2008
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.107.498196
Subject(s) - hyperintensity , medicine , white matter , lesion , magnetic resonance imaging , nuclear medicine , brain size , population , parietal lobe , radiology , pathology , environmental health , psychiatry
MRI-based quantification of gray and white matter volume is common in studies involving elderly patient populations. The aim of the present study was to describe the effects of not accounting for subcortical white matter hyperintensities (WMH) on tissue volumes in Alzheimer Disease patients with varying degrees of WMH (mild: n=19, moderate: n=22, severe: n=18).

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