Spatial Distribution of White-Matter Hyperintensities in Alzheimer Disease, Cerebral Amyloid Angiopathy, and Healthy Aging | Zendy

Christopher M. Holland | Zendy; Eric E. Smith | Zendy; Istvan Csapo | Zendy; M. Edip Gurol | Zendy; Douglas Brylka | Zendy; Ronald Killiany | Zendy; Deborah Blacker | Zendy; Marilyn Albert | Zendy; Charles R.G. Guttmann | Zendy; Steven M. Greenberg | Zendy

Open Access

Spatial Distribution of White-Matter Hyperintensities in Alzheimer Disease, Cerebral Amyloid Angiopathy, and Healthy Aging

Author(s) -

Christopher M. Holland,

Eric E. Smith,

Istvan Csapo,

M. Edip Gurol,

Douglas Brylka,

Ronald Killiany,

Deborah Blacker,

Marilyn Albert,

Charles R.G. Guttmann,

Steven M. Greenberg

Publication year - 2008

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.107.497438

Subject(s) - medicine , cerebral amyloid angiopathy , hyperintensity , alzheimer's disease , white matter , stroke (engine) , pathology , amyloid (mycology) , disease , cardiology , magnetic resonance imaging , dementia , radiology , mechanical engineering , engineering

White-matter hyperintensities (WMHs) detected by magnetic resonance imaging are thought to represent the effects of cerebral small-vessel disease and neurodegenerative changes. We sought to determine whether the spatial distribution of WMHs discriminates between different disease groups and healthy aging individuals and whether these distributions are related to local cerebral perfusion patterns.

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