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Delayed Tolerance With Repetitive Transient Focal Ischemic Preconditioning in the Mouse
Author(s) -
Jian Zhang,
Zeng-Jin Yang,
Judith A. Klaus,
Raymond C. Koehler,
Judy Huang
Publication year - 2008
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.107.497412
Subject(s) - medicine , ischemic preconditioning , transient (computer programming) , stroke (engine) , ischemia , cardiology , anesthesia , mechanical engineering , engineering , computer science , operating system
Transient ischemic attacks have long been regarded as a risk factor for the incidence of stroke but may reduce the severity of stroke by inducing ischemic tolerance. The present objective was to develop an ischemic preconditioning (IPC) model of delayed tolerance in the mouse based on repetitive, transient middle cerebral artery occlusion (MCAO).

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