Emboli Formation Rather Than Inflammatory Mediators Are Responsible for Increased Cerebral Water Content After Conventional and Assisted Beating-Heart Myocardial Revascularization in a Porcine Model | Zendy

Benjamin Bierbach | Zendy; Matthias Meier | Zendy; Walter Kasper-König | Zendy; Axel Heimann | Zendy; Beat Alessandri | Zendy; Georg Horstick | Zendy; H. Oelert | Zendy; Oliver Kempski | Zendy

Open Access

Emboli Formation Rather Than Inflammatory Mediators Are Responsible for Increased Cerebral Water Content After Conventional and Assisted Beating-Heart Myocardial Revascularization in a Porcine Model

Author(s) -

Benjamin Bierbach,

Matthias Meier,

Walter Kasper-König,

Axel Heimann,

Beat Alessandri,

Georg Horstick,

H. Oelert,

Oliver Kempski

Publication year - 2007

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.107.496620

Subject(s) - medicine , proinflammatory cytokine , cardiopulmonary bypass , cerebral blood flow , hemodynamics , anesthesia , embolus , cardiology , blood flow , cardiac surgery , aortic cross clamp , inflammation

Emboli and proinflammatory mediators are suspected of generating cerebral edema after coronary surgery. In contrast to cardiopulmonary bypass (CPB), off-pump coronary artery bypass surgery (OPCAB) reduces microemboli count and proinflammatory mediator release but carries the risk of hemodynamic instability. A microaxial blood pump can augment cardiac output.

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