Retinal Signs and Stroke | Zendy

Michelle L. Baker | Zendy; Peter J. Hand | Zendy; Jie Jin Wang | Zendy; Tien Yin Wong | Zendy

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Retinal Signs and Stroke

Author(s) -

Michelle L. Baker,

Peter J. Hand,

Jie Jin Wang,

Tien Yin Wong

Publication year - 2008

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.107.496091

Subject(s) - medicine , stroke (engine) , retinal , central retinal vein , hypertensive retinopathy , retinopathy , retina , ophthalmology , retinal vein , central retinal vein occlusion , cardiology , diabetes mellitus , macular edema , neuroscience , mechanical engineering , biology , engineering , endocrinology

The retinal and cerebral vasculature share similar anatomic, physiological, and embryological characteristics. We reviewed the literature, focusing particularly on recent population-based studies, to examine the relationship between retinal signs and stroke. Summary of Review- Hypertensive retinopathy signs (eg, focal retinal arteriolar narrowing, arterio-venous nicking) were associated with prevalent stroke, incident stroke, and stroke mortality, independent of blood pressure and other cerebrovascular risk factors. Diabetic retinopathy signs (eg, microaneurysms, hard exudates) were similarly associated with incident stroke and stroke mortality. Retinal arteriolar emboli were associated with stroke mortality but not incident stroke. There were fewer studies on the association of other retinal signs such as retinal vein occlusion and age-related macular degeneration with stroke, and the results were less consistent.

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