Impact of Restricting Enrollment in Stroke Genetics Research to Adults Able to Provide Informed Consent
Author(s) -
Donna T. Chen,
L. Douglas Case,
Thomas G. Brott,
Robert D. Brown,
Scott Silliman,
James F. Meschia,
Bradford B. Worrall
Publication year - 2008
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.107.494518
Subject(s) - medicine , informed consent , stroke (engine) , surrogate endpoint , stroke recovery , cohort , prospective cohort study , physical therapy , pathology , alternative medicine , mechanical engineering , rehabilitation , engineering
The extent of potential consent bias in observational studies elucidating genetic and environmental contributions to ischemic stroke is largely unknown. The purpose of this study was to assess differences in stroke cohort characteristics between those who provided informed consent and those whose enrollment was authorized by surrogate decision makers.
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