Selective Expansion of Influenza A Virus–Specific T Cells in Symptomatic Human Carotid Artery Atherosclerotic Plaques | Zendy

Tymen Keller | Zendy; J. J. van der Meer | Zendy; Peter Teeling | Zendy; Koen van der Sluijs | Zendy; Mirza M. Idu | Zendy; Guus F. Rimmelzwaan | Zendy; Marcel Levi | Zendy; Allard C. van der Wal | Zendy; Onno J. de Boer | Zendy

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Selective Expansion of Influenza A Virus–Specific T Cells in Symptomatic Human Carotid Artery Atherosclerotic Plaques

Author(s) -

Tymen Keller,

J. J. van der Meer,

Peter Teeling,

Koen van der Sluijs,

Mirza M. Idu,

Guus F. Rimmelzwaan,

Marcel Levi,

Allard C. van der Wal,

Onno J. de Boer

Publication year - 2007

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.107.491282

Subject(s) - medicine , virus , inflammation , antigen , influenza a virus , immunology , virology , pathology

Evidence is accumulating that infection with influenza A virus contributes to atherothrombotic disease. Vaccination against influenza decreases the risk of atherosclerotic syndromes, indicating that inflammatory mechanisms may be involved. We tested the hypothesis that influenza A virus-specific T cells contribute to atherosclerotic plaque inflammation, which mediates the onset of plaque rupture.

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