A Whole-Genome Scan for Stroke or Myocardial Infarction in Family Blood Pressure Program Families | Zendy

Richard Sherva | Zendy; Michael B. Miller | Zendy; James S. Pankow | Zendy; Steven C. Hunt | Zendy; Eric Boerwinkle | Zendy; Thomas H. Mosley | Zendy; Alan B. Weder | Zendy; J. David Curb | Zendy; Amy Luke | Zendy; Alanna C. Morrison | Zendy; Myriam Fornage | Zendy; Donna K. Arnett | Zendy

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A Whole-Genome Scan for Stroke or Myocardial Infarction in Family Blood Pressure Program Families

Author(s) -

Richard Sherva,

Michael B. Miller,

James S. Pankow,

Steven C. Hunt,

Eric Boerwinkle,

Thomas H. Mosley,

Alan B. Weder,

J. David Curb,

Amy Luke,

Alanna C. Morrison,

Myriam Fornage,

Donna K. Arnett

Publication year - 2008

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.107.490433

Subject(s) - medicine , stroke (engine) , blood pressure , myocardial infarction , cardiology , ischemic stroke , genome , genetics , gene , ischemia , mechanical engineering , biology , engineering

Atherothrombotic diseases, including stroke and myocardial infarction, share a common pathogenesis. Chromosomal regions have been linked to atherothrombotic diseases in family studies, and association studies have identified candidate gene polymorphisms that affect the risk of stroke and/or myocardial infarction. Using data from the Family Blood Pressure Program, we tested for chromosomal regions linked to the composite phenotype of stroke or myocardial infarction in a large set of hypertensive families.

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