Impaired Endothelial Function of Forearm Resistance Arteries in CADASIL Patients | Zendy

A. Stenborg | Zendy; Hannu Kalimo | Zendy; Matti Viitanen | Zendy; Andreas Terént | Zendy; Lars Lind | Zendy

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Impaired Endothelial Function of Forearm Resistance Arteries in CADASIL Patients

Author(s) -

A. Stenborg,

Hannu Kalimo,

Matti Viitanen,

Andreas Terént,

Lars Lind

Publication year - 2007

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.107.490029

Subject(s) - cadasil , medicine , vasodilation , forearm , brachial artery , cardiology , leukoencephalopathy , endothelium , vascular resistance , anesthesia , hemodynamics , anatomy , blood pressure , disease

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a hereditary arteriopathy, which mainly involves the brain causing stroke and dementia. Mice expressing the mutated protein display early dysfunction in vasoreactivity in resistance arteries, but studies of patients have been inconclusive so far.

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