Enhanced Detection of Thromboemboli With the Use of Targeted Microbubbles | Zendy

Matthew Martin | Zendy; Emma M.L. Chung | Zendy; Alison H. Goodall | Zendy; Alberto Della Martina | Zendy; Kumar V. Ramnarine | Zendy; Lingke Fan | Zendy; S. V. Hainsworth | Zendy; A. Ross Naylor | Zendy; David H. Evans | Zendy

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Enhanced Detection of Thromboemboli With the Use of Targeted Microbubbles

Author(s) -

Matthew Martin,

Emma M.L. Chung,

Alison H. Goodall,

Alberto Della Martina,

Kumar V. Ramnarine,

Lingke Fan,

S. V. Hainsworth,

A. Ross Naylor,

David H. Evans

Publication year - 2007

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.107.489435

Subject(s) - microbubbles , thrombus , medicine , pulsatile flow , transcranial doppler , ultrasound , biomedical engineering , radiology , cardiology

Targeted ultrasound contrast agents have recently been developed to adhere selectively to specific pathogenic materials such as plaque or thrombus. Administration of such microbubbles has potential to aid transcranial Doppler ultrasound (TCD) detection of emboli and to act as markers for distinguishing one embolic material from another. The purpose of this study was to investigate whether TCD detection of circulating thrombus emboli would be enhanced by the addition of targeted microbubbles.

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