Long-Term Neuroblast Migration Along Blood Vessels in an Area With Transient Angiogenesis and Increased Vascularization After Stroke | Zendy

Pär Thored | Zendy; James Wood | Zendy; Andreas Arvidsson | Zendy; Jörg Cammenga | Zendy; Zaal Kokaia | Zendy; Olle Lindvall | Zendy

Open Access

Long-Term Neuroblast Migration Along Blood Vessels in an Area With Transient Angiogenesis and Increased Vascularization After Stroke

Author(s) -

Pär Thored,

James Wood,

Andreas Arvidsson,

Jörg Cammenga,

Zaal Kokaia,

Olle Lindvall

Publication year - 2007

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.107.488445

Subject(s) - neuroblast , angiogenesis , subventricular zone , neurogenesis , medicine , progenitor cell , rostral migratory stream , pathology , arteriogenesis , stroke (engine) , neovascularization , anatomy , stem cell , neuroscience , biology , microbiology and biotechnology , mechanical engineering , engineering

Stroke induced by middle cerebral artery occlusion (MCAO) causes long-term formation of new striatal neurons from stem/progenitor cells in the subventricular zone (SVZ). We explored whether MCAO leads to hypoxia, changes in vessel density, and angiogenesis in the ipsilateral SVZ and adjacent striatum, and determined the relation between the migrating neuroblasts and the vasculature.

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