Open AccessEdaravone Attenuates Brain Edema and Neurologic Deficits in a Rat Model of Acute Intracerebral Hemorrhage
Author(s) -
Takehiro Nakamura,
Yasuhiro Kuroda,
Susumu Yamashita,
Xia Zhang,
Osamu Miyamoto,
Takashi Tamiya,
Seigo Nagao,
Guohua Xi,
Richard F. Keep,
Toshifumi Itano
Publication year - 2007
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.107.486654
Subject(s) - edaravone , medicine , intracerebral hemorrhage , anesthesia , free radical scavenger , pharmacology , oxidative stress , subarachnoid hemorrhage
Our previous studies have demonstrated that oxidative DNA injury occurs in the brain after intracerebral hemorrhage (ICH). We therefore examined whether edaravone, a free-radical scavenger, could reduce ICH-induced brain injury.
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