Lesion Volume Change After Treatment With Tissue Plasminogen Activator Can Discriminate Clinical Responders From Nonresponders | Zendy

José G. Merino | Zendy; Lawrence L. Latour | Zendy; Jason W. Todd | Zendy; Marie Luby | Zendy; Peter D. Schellinger | Zendy; DongWha Kang | Zendy; Steven Warach | Zendy

Open Access

Lesion Volume Change After Treatment With Tissue Plasminogen Activator Can Discriminate Clinical Responders From Nonresponders

Author(s) -

José G. Merino,

Lawrence L. Latour,

Jason W. Todd,

Marie Luby,

Peter D. Schellinger,

DongWha Kang,

Steven Warach

Publication year - 2007

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.107.485995

Subject(s) - medicine , tissue plasminogen activator , lesion , thrombolysis , t plasminogen activator , stroke (engine) , plasminogen activator , pathology , cardiology , gastroenterology , myocardial infarction , mechanical engineering , engineering

A change in acute-to-chronic lesion volume has been proposed as a biomarker for stroke therapies. The objectives of this study were to determine the magnitude of lesion volume change after standard treatment with tissue plasminogen activator and to determine whether specific volume change thresholds can discriminate clinical responders from nonresponders.

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