Is There a Direct Link Between Cerebrovascular Activity and Cerebrospinal Fluid Pressure-Volume Compensation? | Zendy

Christina Haubrich | Zendy; Zofia Czosnyka | Zendy; Andrea Lavinio | Zendy; Peter Smielewski | Zendy; Rolf R. Diehl | Zendy; John D. Pickard | Zendy; Marek Czosnyka | Zendy

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Is There a Direct Link Between Cerebrovascular Activity and Cerebrospinal Fluid Pressure-Volume Compensation?

Author(s) -

Christina Haubrich,

Zofia Czosnyka,

Andrea Lavinio,

Peter Smielewski,

Rolf R. Diehl,

John D. Pickard,

Marek Czosnyka

Publication year - 2007

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.107.485847

Subject(s) - medicine , cerebral blood flow , cerebral perfusion pressure , cerebral autoregulation , cerebrospinal fluid , middle cerebral artery , intracranial pressure , cerebral arteries , autoregulation , anesthesia , transcranial doppler , perfusion , cardiology , blood flow , blood pressure , ischemia

Cerebral blood flow is coupled to brain metabolism by means of active modulation of cerebrovascular resistance. This homeostatic vasogenic activity is reflected in slow waves of cerebral blood flow velocities (FV) which can also be detected in intracranial pressure (ICP). However, effects of increased ICP on the modulation of cerebral blood flow are still poorly understood. This study focused on the question whether ICP has an independent impact on slow waves of FV within the normal cerebral perfusion pressures range.

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