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Delayed Postischemic Treatment With Fluvastatin Improved Cognitive Impairment After Stroke in Rats
Author(s) -
Munehisa Shimamura,
Naoyuki Sato,
Masataka Sata,
Hitomi Kurinami,
Daisuke Takeuchi,
Kouji Wakayama,
Takuya Hayashi,
Hidehiro Iida,
Ryuichi Morishita
Publication year - 2007
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.107.485045
Subject(s) - fluvastatin , medicine , stroke (engine) , infarction , cerebral infarction , neuroprotection , ischemia , endocrinology , anesthesia , cardiology , urology , myocardial infarction , mechanical engineering , engineering , simvastatin
Recent clinical evidences indicate that statins may have beneficial effects on the functional recovery after ischemic stroke. However, the effect of delayed postischemic treatment with statins is still unclear. In the present study, we evaluated the effects of fluvastatin in the chronic stage of cerebral infarction in a rat model.

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