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MRI-Based and CT-Based Thrombolytic Therapy in Acute Stroke Within and Beyond Established Time Windows
Author(s) -
Peter D. Schellinger,
Götz Thomalla,
Jens Fiehler,
Martin Köhrmann,
Carlos A. Molina,
Tobias NeumannHaefelin,
Marc Ribó,
Oliver C. Singer,
Olivier ZaroWeber,
Jan Sobesky
Publication year - 2007
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.107.483255
Subject(s) - medicine , thrombolysis , modified rankin scale , stroke (engine) , multivariate analysis , randomized controlled trial , acute stroke , univariate analysis , surgery , ischemic stroke , tissue plasminogen activator , ischemia , mechanical engineering , myocardial infarction , engineering
The use of intravenous thrombolysis is restricted to a minority of patients by the rigid 3-hour time window. This window may be extended by using modern imaging-based selection algorithms. We assessed safety and efficacy of MRI-based thrombolysis within and beyond 3 hours compared with standard CT-based thrombolysis.

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