CRP Gene Haplotypes, Serum CRP, and Cerebral Small-Vessel Disease | Zendy

Christiane Reitz | Zendy; Klaus Berger | Zendy; Moniek P.M. de Maat | Zendy; Monika Stoll | Zendy; Frauke Friedrichs | Zendy; Isabella Kardys | Zendy; Jacqueline C.M. Witteman | Zendy; Monique M.B. Breteler | Zendy

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CRP Gene Haplotypes, Serum CRP, and Cerebral Small-Vessel Disease

Author(s) -

Christiane Reitz,

Klaus Berger,

Moniek P.M. de Maat,

Monika Stoll,

Frauke Friedrichs,

Isabella Kardys,

Jacqueline C.M. Witteman,

Monique M.B. Breteler

Publication year - 2007

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.107.482661

Subject(s) - haplotype , medicine , pathogenesis , leukoaraiosis , c reactive protein , pathology , single nucleotide polymorphism , disease , genotype , gene , genetics , inflammation , biology , dementia

It remains unclear whether C-reactive protein (CRP) is a serum marker for atherothrombotic disease or a causal factor in the pathogenesis of atherosclerosis. We explored the association between CRP gene variations and cerebral small-vessel disease (SVD) in the Rotterdam Scan Study (N=1035) and the MEMO Study (N=268).

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