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An Interactive Association of Common Sequence Variants in the Neuropeptide Y Gene With Susceptibility to Ischemic Stroke
Author(s) -
Chaeyoung Lee,
Minyoung Kong
Publication year - 2007
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.107.482075
Subject(s) - haplotype , medicine , linkage disequilibrium , stroke (engine) , allele , candidate gene , single nucleotide polymorphism , genetic association , ischemic stroke , case control study , genetics , bioinformatics , gene , genotype , ischemia , biology , engineering , mechanical engineering
Knowledge of the genetic architecture of ischemic stroke has been quite limited. Most significant associations of candidate genes with ischemic stroke have been difficult to replicate. This might be because the associations were not strong enough for results to be consistent, and testing a mixture of heterogeneous ischemic strokes might lead to confounded genetic associations.

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