A Randomized Controlled Trial of Hydrocortisone Against Hyponatremia in Patients With Aneurysmal Subarachnoid Hemorrhage | Zendy

Yoichi Katayama | Zendy; Jo Haraoka | Zendy; Hidehiro Hirabayashi | Zendy; Tatsuro Kawamata | Zendy; Keiji Kawamoto | Zendy; Takao Kitahara | Zendy; Jun Kojima | Zendy; Toshihiko Kuroiwa | Zendy; Tatsuro Mori | Zendy; Nobuhiro Moro | Zendy; Izumi Nagata | Zendy; Akira Ogawa | Zendy; Kikuo Ohno | Zendy; Yoshikatsu Seiki | Zendy; Yoshiaki Shiokawa | Zendy; Akira Teramoto | Zendy; Teiji Tominaga | Zendy; Toshiki Yoshimine | Zendy

Open Access

A Randomized Controlled Trial of Hydrocortisone Against Hyponatremia in Patients With Aneurysmal Subarachnoid Hemorrhage

Author(s) -

Yoichi Katayama,

Jo Haraoka,

Hidehiro Hirabayashi,

Tatsuro Kawamata,

Keiji Kawamoto,

Takao Kitahara,

Jun Kojima,

Toshihiko Kuroiwa,

Tatsuro Mori,

Nobuhiro Moro,

Izumi Nagata,

Akira Ogawa,

Kikuo Ohno,

Yoshikatsu Seiki,

Yoshiaki Shiokawa,

Akira Teramoto,

Teiji Tominaga,

Toshiki Yoshimine

Publication year - 2007

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.106.480038

Subject(s) - medicine , hydrocortisone , hyponatremia , natriuresis , placebo , subarachnoid hemorrhage , randomized controlled trial , anesthesia , gastroenterology , urology , blood pressure , alternative medicine , pathology

Hyponatremia is common after aneurysmal subarachnoid hemorrhage (SAH). It is caused by natriuresis, which induces osmotic diuresis and decreases blood volume, contributing to symptomatic cerebral vasospasm (SCV). Hypervolemic therapy to prevent SCV will not be efficient under this condition. We conducted a randomized controlled trial to assess the efficacy of hydrocortisone, which promotes sodium retention in the kidneys.

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