Adipophilin Expression Is Increased in Symptomatic Carotid Atherosclerosis
Author(s) -
Krista Nuotio,
Pia M. Isoviita,
Jani Saksi,
Petra Ijäs,
Janne Pitkäniemi,
Riitta Sonninen,
Lauri Soinne,
Eija Saimanen,
Oili Salonen,
Petri T. Kovanen,
Markku Kaste,
Perttu J. Lindsberg
Publication year - 2007
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.106.478867
Subject(s) - medicine , cd68 , pathology , immunohistochemistry , asymptomatic , abca1 , atheroma , cholesterol , endocrinology , gene , biology , biochemistry , transporter
Adipophilin is an adipose differentiation-related protein expressed in lipid-containing cells. Using DNA microarray analysis, we previously found the adipophilin gene (ADFP) to be overexpressed in symptomatic carotid plaques (CP). This led us to further examine the role of adipophilin in carotid atherosclerosis relative to symptom status.
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