Brain Atrophy Is Related to Lacunar Lesions and Tissue Microstructural Changes in CADASIL
Author(s) -
Éric Jouvent,
Anand Viswanathan,
JeanFrançois Mangin,
Michael O’Sullivan,
JeanPierre Guichard,
Andreas Gschwendtner,
R. Cumurciuc,
F. Buffon,
Nils Peters,
Chahin Pachaï,
MarieGermaine Bousser,
Martin Dichgans,
Hugues Chabriat
Publication year - 2007
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.106.478263
Subject(s) - cadasil , medicine , lacunar stroke , atrophy , pathology , lacunar infarction , stroke (engine) , leukoencephalopathy , ischemic stroke , disease , cardiology , ischemia , cerebral infarction , mechanical engineering , engineering
Cerebral atrophy has been recently recognized as a key marker of disease progression in cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). The contribution of subcortical cerebral lesions in this process remains undetermined. The aim of this study was to investigate the relationships between cerebral volume and different types of subcortical MRI lesions in CADASIL.
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