Effect of Gender on NADPH-Oxidase Activity, Expression, and Function in the Cerebral Circulation
Author(s) -
Alyson A. Miller,
Grant R. Drummond,
A Mast,
Harald Schmidt,
Christopher G. Sobey
Publication year - 2007
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.106.477406
Subject(s) - nadph oxidase , nox4 , superoxide , nox1 , medicine , endocrinology , ovariectomized rat , superoxide dismutase , sod2 , p22phox , cerebral circulation , lucigenin , oxidative stress , chemistry , biochemistry , estrogen , enzyme
This study tested whether NADPH-oxidase activity, expression, and functional effects on vascular tone are influenced by gender in the rat cerebral circulation and whether such differences are estrogen-dependent.
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