Open AccessBrain Repair by Hematopoietic Growth Factors in a Rat Model of Stroke
Author(s) -
Li-Ru Zhao,
Seema Singhal,
Wei-Ming Duan,
Jayesh Mehta,
John A. Kessler
Publication year - 2007
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.106.476457
Subject(s) - medicine , stroke (engine) , haematopoiesis , neuroscience , surgery , genetics , stem cell , biology , mechanical engineering , engineering
Stem cell factor (SCF) and granulocyte-colony stimulating factor (G-CSF) are essential growth factors in hematopoiesis. We determined whether receptors for SCF and G-CSF exist in the brain and whether exogenous SCF and G-CSF are beneficial to brain repair after brain ischemia.
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