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Effects of Poststroke Losartan Versus Captopril Treatment on Myogenic and Endothelial Function in the Cerebrovasculature of SHRsp
Author(s) -
John S. Smeda,
John J. McGuire
Publication year - 2007
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.106.475087
Subject(s) - medicine , captopril , bradykinin , losartan , vasodilation , middle cerebral artery , myograph , endocrinology , cerebral arteries , blood pressure , stroke (engine) , nitric oxide synthase , anesthesia , nitric oxide , angiotensin ii , ischemia , receptor , mechanical engineering , engineering
We assessed the ability of poststroke captopril and losartan treatment to reverse myogenic and endothelial dysfunction in the middle cerebral arteries of Kyoto-Wistar stroke-prone spontaneously hypertensive rats (SHRsp) that developed intracerebral hemorrhagic stroke.

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