Disinhibition of the Premotor Cortex Contributes to a Maladaptive Change in the Affected Hand After Stroke | Zendy

Naoyuki Takeuchi | Zendy; Takeo Tada | Zendy; Takayo Chuma | Zendy; Yuichiro Matsuo | Zendy; Katsunori Ikoma | Zendy

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Disinhibition of the Premotor Cortex Contributes to a Maladaptive Change in the Affected Hand After Stroke

Author(s) -

Naoyuki Takeuchi,

Takeo Tada,

Takayo Chuma,

Yuichiro Matsuo,

Katsunori Ikoma

Publication year - 2007

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.106.470187

Subject(s) - transcranial magnetic stimulation , disinhibition , motor cortex , medicine , stroke (engine) , premotor cortex , inhibitory postsynaptic potential , silent period , primary motor cortex , physical medicine and rehabilitation , motor function , neuroscience , motor system , stimulation , psychology , anatomy , dorsum , mechanical engineering , engineering

The mechanism of reorganization after stroke remains uncertain. Several studies that have measured reaction time (RT) delay by transcranial magnetic stimulation (TMS) have revealed some substrates responsible for the reorganization of motor recovery. In this study, we evaluated the RT delay and inhibitory functions by examining the silent period (SP) in the primary motor cortex (M1) and premotor cortex (PMC) of the affected hemisphere. Using these data, we investigated whether a change in the inhibitory system might influence motor recovery.

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