English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

119 Background and Purpose: To assess the effect of  concurrent arterial aneurysms on the risk of hemorrhagic presentation  in brain arteriovenous malformations (AVMs).Methods: The  463 consecutive, prospectively enrolled patients from the New York AVM  Databank were analyzed. Concurrent arterial aneurysms on brain  angiography were classified as (1) flow-related feeding artery  aneurysms, (2) intranidal aneurysms, and (3) aneurysms unrelated to  blood flow to the AVM. Clinical presentation (diagnostic event) was  categorized as (1) intracranial hemorrhage proven by imaging or (2)  non-hemorrhagic presentation. Univariate and multivariate statistical  models were applied to test the effect of age, gender, AVM size, venous  drainage pattern, and the three different types of aneurysms on the  risk of AVM hemorrhage at initial presentation.Results: Arterial aneurysms were found in 117 (25%) AVM patients. In 93 cases,  a single aneurysm type was found (54 had feeding artery aneurysms,  21showed intranidal aneurysms, 18 had unrelated aneurysms), 24 patients  had more than one aneurysm type. Overall, 204 (44%) patients presented  with hemorrhage. Concurrent arterial aneurysms were significantly more  frequent in patients with incident AVM hemorrhage (34%) as compared to  those without hemorrhage (18%, p=0.001). In the multivariate model an  independent effect for flow-related aneurysms (OR 2.1 , 95% CI: 1.2 to  3.8) on hemorrhagic AVM presentation was found. No effect was seen for  intranidal and unrelated aneurysms. The attributable risk of incident  hemorrhage in AVM patients harbouring flow-related aneurysms is 0.059  (95% CI: 0.01 to 0.105).Conclusions: The findings suggest  that flow-related arterial aneurysms are an independent determinant for  increased risk of incident AVM hemorrhage.

The Effect of Concurrent Arterial Aneurysms on the Risk of Hemorrhagic Presentation in Brain Arteriovenous Malformations