Lucigenin Chemiluminescence Assay for Superoxide Detection | Zendy

Igor B. Afanasʹev | Zendy

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Lucigenin Chemiluminescence Assay for Superoxide Detection

Author(s) -

Igor B. Afanasʹev

Publication year - 2001

Publication title -

circulation research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.899

H-Index - 336

eISSN - 1524-4571

pISSN - 0009-7330

DOI - 10.1161/res.89.11.e46

Subject(s) - lucigenin , chemiluminescence , superoxide , chemistry , microbiology and biotechnology , biochemistry , biology , chromatography , enzyme

To the Editor:The recent review by Tarpey and Fridovich published in Circulation Research 1 mostly contains interesting and sound material; however, I would like to comment on the section entitled, “Superoxide Detection, Chemiluminescence Reactions.” Basing mainly on their own data,2 authors maintain that lucigenin-amplified chemiluminescence (LucCL) overestimates the rate of superoxide production due to the redox cycling of lucigenin. Taking into account that …

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