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Cerebrovascular Events in Patients With Significant Stenosis of the Carotid Artery Are Associated With Hyperhomocysteinemia and Platelet Antigen-1 (Leu33Pro) Polymorphism
Author(s) -
Jonathan Y. Streifler,
Nurit Rosenberg,
Angela Chetrit,
Regina Eskaraev,
BenAmi Sela,
Rima Dardik,
Ariella Zivelin,
B. Ravid,
Jacqueline Davidson,
Uri Seligsohn,
Aida Inbal
Publication year - 2001
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/hs1201.099650
Subject(s) - medicine , hyperhomocysteinemia , asymptomatic , homocysteine , gastroenterology , odds ratio , risk factor , stenosis , cardiology , stroke (engine) , surgery , engineering , mechanical engineering
Although risk factors for carotid artery stenosis caused by atherosclerosis are known, it is unclear what triggers "activation" of the atherosclerotic plaques and the ensuing thromboembolic cerebral events. The aim of this study was to evaluate whether thrombophilic factors, platelet glycoprotein (GP) polymorphisms, and homocysteine are associated with a risk of ischemic events in patients with significant carotid stenosis.

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