Sphingosine 1-Phosphate Contracts Canine Basilar Arteries In Vitro and In Vivo | Zendy

Masahiko Tosaka | Zendy; Fumikazu Okajima | Zendy; Yasuhiro Hashiba | Zendy; Nobuhito Saito | Zendy; Takuro Nagano | Zendy; Takashi Watanabe | Zendy; Takao Kimura | Zendy; Tomio Sasaki | Zendy

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Sphingosine 1-Phosphate Contracts Canine Basilar Arteries In Vitro and In Vivo

Author(s) -

Masahiko Tosaka,

Fumikazu Okajima,

Yasuhiro Hashiba,

Nobuhito Saito,

Takuro Nagano,

Takashi Watanabe,

Takao Kimura,

Tomio Sasaki

Publication year - 2001

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/hs1201.099525

Subject(s) - basilar artery , medicine , subarachnoid hemorrhage , cisterna magna , sphingosine , in vivo , vasospasm , cerebral vasospasm , in vitro , sphingosine 1 phosphate , pharmacology , cerebrospinal fluid , biology , biochemistry , receptor , microbiology and biotechnology

Sphingosine 1-phosphate (S1P) is a platelet-derived bioactive lipid that exerts a variety of biological responses, including vasocontraction. To understand the involvement of S1P in cerebral vasospasm, we investigated the effect of S1P on vasocontraction of the canine basilar artery in vitro and in vivo.

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