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Plasma Concentration of C-Reactive Protein and Risk of Ischemic Stroke and Transient Ischemic Attack: The Framingham Study
Author(s) -
Natalia S. Rost,
Philip A. Wolf,
Carlos S. Kase,
Margaret KellyHayes,
Halit Silbershatz,
Joseph M. Massaro,
Ralph B. D’Agostino,
Carl Franzblau,
Peter W.F. Wilson
Publication year - 2001
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/hs1101.098151
Subject(s) - medicine , quartile , framingham risk score , stroke (engine) , c reactive protein , diabetes mellitus , relative risk , blood pressure , cohort , cardiology , risk factor , disease , endocrinology , confidence interval , inflammation , mechanical engineering , engineering
The role of C-reactive protein (CRP) as a novel plasma marker of atherothrombotic disease is currently under investigation. Previous studies have mostly related CRP to coronary heart disease, were often restricted to a case-control design, and failed to include pertinent risk factors to evaluate the joint and net effect of CRP on the outcome. We related plasma CRP levels to incidence of first ischemic stroke or transient ischemic attack (TIA) in the Framingham Study original cohort.

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