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Nimodipine in Animal Model Experiments of Focal Cerebral Ischemia
Author(s) -
Janneke Horn,
Rob J. de Haan,
Marijn A. Vermeulen,
Paul G.M. Luiten,
M. Limburg
Publication year - 2001
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/hs1001.096009
Subject(s) - nimodipine , medicine , animal studies , clinical trial , stroke (engine) , ischemia , animal model , anesthesia , human studies , experimental animal , medline , calcium , mechanical engineering , political science , veterinary medicine , law , engineering
Based on the results of animal experiments, clinical trials were performed with nimodipine, which did not demonstrate a beneficial effect on outcome after stroke. The aim of this study was to determine whether the evidence from animal experiments with nimodipine supported the use of nimodipine in clinical trials.

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