Early Carotid Endarterectomy for Critical Carotid Artery Stenosis After Thrombolysis Therapy in Acute Ischemic Stroke in the Middle Cerebral Artery | Zendy

Christopher McPherson | Zendy; Daniel Woo | Zendy; Paul L. Cohen | Zendy; Arthur Pancioli | Zendy; Brett Kissela | Zendy; Janice Carrozzella | Zendy; Thomas A. Tomsick | Zendy; Mario Zuccarello | Zendy

Open Access

Early Carotid Endarterectomy for Critical Carotid Artery Stenosis After Thrombolysis Therapy in Acute Ischemic Stroke in the Middle Cerebral Artery

Author(s) -

Christopher McPherson,

Daniel Woo,

Paul L. Cohen,

Arthur Pancioli,

Brett Kissela,

Janice Carrozzella,

Thomas A. Tomsick,

Mario Zuccarello

Publication year - 2001

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/hs0901.095679

Subject(s) - medicine , carotid endarterectomy , stenosis , thrombolysis , stroke (engine) , surgery , middle cerebral artery , endarterectomy , tissue plasminogen activator , cardiology , ischemia , myocardial infarction , mechanical engineering , engineering

Tissue plasminogen activator (tPA) has been shown to be effective for acute ischemic stroke. However, if a high-grade cervical carotid stenosis remains despite tPA therapy, patients are at risk for recurrent stroke. Carotid endarterectomy (CEA) has been shown to be effective in symptomatic patients with high-grade cervical carotid stenosis in reducing the risk of stroke, but it is unknown whether CEA can be performed safely after tPA thrombolysis. We describe our experience with 5 patients who underwent early (<48 hours) CEA for residual high-grade cervical carotid stenosis after thrombolytic therapy for acute ischemic stroke in the middle cerebral artery territory.

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