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Behavioral/Environmental Intervention Improves Learning After Cerebral Hypoxia-Ischemia in Rats
Author(s) -
IChing Chou,
Tatyana Trakht,
Carina Signori,
J. Hayden Smith,
Barbara T. Felt,
Delia M. Vázquez,
John Barks
Publication year - 2001
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/hs0901.095656
Subject(s) - medicine , hippocampal formation , morris water navigation task , hypoxia (environmental) , ischemia , brain damage , anesthesia , analysis of variance , cerebral hypoxia , water maze , hippocampus , environmental enrichment , physiology , chemistry , organic chemistry , oxygen
In premature infants, many of whom experience ischemic brain insults, the environment of rearing influences cognitive outcome. We developed a model to evaluate the effect of rearing conditions on learning after unilateral cerebral hypoxia-ischemia (HI) in 7-day-old (P7) rats. We hypothesized that neonatal handling would benefit rats recovering from an episode of HI.

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