Bone Morphogenetic Protein-6 Reduces Ischemia-Induced Brain Damage in Rats | Zendy

Yun Wang | Zendy; Chen-Fu Chang | Zendy; Marisela Morales | Zendy; Jenny Chou | Zendy; HuiLing Chen | Zendy; YungHsiao Chiang | Zendy; ShinnZong Lin | Zendy; Jean Lud Cadet | Zendy; Xiaolin Deng | Zendy; JiaYi Wang | Zendy; Su-Yu Chen | Zendy; Paul L. Kaplan | Zendy; Barry J. Hoffer | Zendy

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Bone Morphogenetic Protein-6 Reduces Ischemia-Induced Brain Damage in Rats

Author(s) -

Yun Wang,

Chen-Fu Chang,

Marisela Morales,

Jenny Chou,

HuiLing Chen,

YungHsiao Chiang,

ShinnZong Lin,

Jean Lud Cadet,

Xiaolin Deng,

JiaYi Wang,

Su-Yu Chen,

Paul L. Kaplan,

Barry J. Hoffer

Publication year - 2001

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/hs0901.095650

Subject(s) - medicine , ischemia , bone morphogenetic protein , stroke (engine) , brain damage , bone morphogenetic protein 2 , surgery , biochemistry , gene , in vitro , mechanical engineering , chemistry , engineering

Bone morphogenetic protein-6 (BMP6) and its receptors are expressed in adult and fetal brain. Receptors for BMP6 are upregulated in adult brain after injury, leading to the suggestion that BMP6 is involved in the physiological response to neuronal injury. The purpose of this study was to determine whether there was a neuroprotective effect of BMP6 in vivo and in vitro.

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