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The presence of Chlamydia pneumoniae has been reported in carotid atheroma, but its causative effect in the activation of an atherosclerotic plaque to a prothrombotic state remains unproved. Antigen- mediated activation of T lymphocytes within plaque may represent a mechanism by which infection can result in plaque conversion. The goal of the present study was to characterize the T-cell subtype profile related to the presence of C pneumoniae in patients with symptomatic versus asymptomatic carotid atherosclerosis.

Increased CD8+T Cells Associated WithChlamydia pneumoniaein Symptomatic Carotid Plaque

Increased CD8⁺T Cells Associated WithChlamydia pneumoniaein Symptomatic Carotid Plaque