Open AccessAcute Tissue Damage After Injections of Thrombin and Plasmin into Rat Striatum
Author(s) -
Mengzhou Xue,
Marc R. Del Bigio
Publication year - 2001
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/hs0901.095408
Subject(s) - medicine , tissue plasminogen activator , plasmin , extravasation , intracerebral hemorrhage , thrombin , pathology , pharmacology , platelet , biology , biochemistry , subarachnoid hemorrhage , enzyme
Extravasation of blood is associated with intracerebral hemorrhage and head trauma. The mechanism of brain cell injury associated with hemorrhage differs from that due to pure ischemia. The purpose of this study was to investigate the acute changes after intracerebral injections of proteins that are involved in blood clotting and clot lysis.
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