Safety of Intraventricular Sodium Nitroprusside and Thiosulfate for the Treatment of Cerebral Vasospasm in the Intensive Care Unit Setting | Zendy

Jeffrey E. Thomas | Zendy; Gerri McGinnis | Zendy

Open Access

Safety of Intraventricular Sodium Nitroprusside and Thiosulfate for the Treatment of Cerebral Vasospasm in the Intensive Care Unit Setting

Author(s) -

Jeffrey E. Thomas,

Gerri McGinnis

Publication year - 2002

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/hs0202.103410

Subject(s) - medicine , anesthesia , vasospasm , cerebral vasospasm , subarachnoid hemorrhage , intracranial pressure , intraventricular hemorrhage , transcranial doppler , sodium nitroprusside , cardiology , pregnancy , nitric oxide , biology , genetics , gestational age

We have recently reported the safety of intraventricular sodium nitroprusside for the treatment of cerebral ischemia from vasospasm. Treatments have been accompanied previously by cerebral angiography to gauge treatment effect on established vasospasm. We presently report the safe coadministration of intraventricular sodium nitroprusside and thiosulfate in 10 patients with secured ruptured cerebral aneurysms in the intensive care unit, without the use of cerebral angiography for vasospasm treatment.

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