Effect of Controlled Release/Extended Release Metoprolol on Carotid Intima-Media Thickness in Patients With Hypercholesterolemia | Zendy

Olov Wiklund | Zendy; Johannes Hulthe | Zendy; John Wikstrand | Zendy; Caroline Schmidt | Zendy; SvenOlof Olofsson | Zendy; Göran Bondjers | Zendy

Open Access

Effect of Controlled Release/Extended Release Metoprolol on Carotid Intima-Media Thickness in Patients With Hypercholesterolemia

Author(s) -

Olov Wiklund,

Johannes Hulthe,

John Wikstrand,

Caroline Schmidt,

SvenOlof Olofsson,

Göran Bondjers

Publication year - 2002

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/hs0202.102332

Subject(s) - medicine , metoprolol , placebo , randomization , cardiology , concomitant , intima media thickness , randomized controlled trial , aspirin , common carotid artery , stroke (engine) , cholesterol , beta blocker , gastroenterology , carotid arteries , alternative medicine , pathology , mechanical engineering , heart failure , engineering

Beta-adrenergic blockade has in several studies been shown to improve survival after myocardial infarction. In animal experiments beta-blockers have also shown an antiatherosclerotic effect. The aim of this study was to test the hypothesis that the beta-blocker metoprolol succinate controlled release/extended release (CR/XL), when given to patients with hypercholesterolemia on concomitant lipid-lowering therapy, provides an additional antiatherosclerotic effect to that provided by the statins, measured as carotid intima-media thickness (IMT).

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research