Acute Intravenous–Intra-Arterial Revascularization Therapy for Severe Ischemic Stroke | Zendy

Michael D. Hill | Zendy; Philip A. Barber | Zendy; Andrew M. Demchuk | Zendy; Nancy Newcommon | Zendy; Andrea Cole-Haskayne | Zendy; Karla J. Ryckborst | Zendy; Laurel Sopher | Zendy; Allison Button | Zendy; William Hu | Zendy; Mark E. Hudon | Zendy; William Morrish | Zendy; Richard Frayne | Zendy; Robert J. Sevick | Zendy; Alastair M. Buchan | Zendy

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Acute Intravenous–Intra-Arterial Revascularization Therapy for Severe Ischemic Stroke

Author(s) -

Michael D. Hill,

Philip A. Barber,

Andrew M. Demchuk,

Nancy Newcommon,

Andrea Cole-Haskayne,

Karla J. Ryckborst,

Laurel Sopher,

Allison Button,

William Hu,

Mark E. Hudon,

William Morrish,

Richard Frayne,

Robert J. Sevick,

Alastair M. Buchan

Publication year - 2002

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/hs0102.101900

Subject(s) - medicine , stroke (engine) , revascularization , ischemic stroke , arterial ischemic stroke , cardiology , ischemia , anesthesia , surgery , myocardial infarction , mechanical engineering , engineering

Intravenous alteplase for acute ischemic stroke is least efficacious for patients with proximal large-artery occlusions and clinically severe strokes. Intra-arterial therapy has the theoretical advantage of establishing a neurovascular diagnosis and high symptomatic artery patency rate but the disadvantage of requiring extra time and technical expertise. A combination of these two approaches may provide the best chance of improving outcome in severe acute ischemic stroke. We sought to assess the safety and feasibility of this approach.

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