Open AccessInhibition of Glutamate Release via Recovery of ATP Levels Accounts for a Neuroprotective Effect of Aspirin in Rat Cortical Neurons Exposed to Oxygen-Glucose Deprivation
Author(s) -
Javier de Cristóbal,
Antonio Cárdenas,
Ignacio Lizasoaín,
Juan C. Leza,
Paz Fernández-Tomé,
Pedro Lorenzo,
Marı́a A. Moro
Publication year - 2002
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/hs0102.101299
Subject(s) - neuroprotection , aspirin , glutamate receptor , pharmacology , medicine , mitochondrion , biochemistry , anesthesia , chemistry , receptor
Aspirin is preventive against stroke not only because of its antithrombotic properties but also by other direct effects. The aim of this study was to elucidate its direct neuroprotective effects.
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