Open AccessActivation Delay After Premature Stimulation in Chronically Diseased Human Myocardium Relates to the Architecture of Interstitial Fibrosis
Author(s) -
Tokuhiro Kawara,
Richard Derksen,
Joris R. de Groot,
Ruben Coronel,
Sara Tasseron,
André C. Linnenbank,
Richard N.W. Hauer,
Hans Kirkels,
Michiel J. Janse,
Jacques M.T. de Bakker
Publication year - 2001
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/hc5001.100833
Subject(s) - medicine , fibrosis , cardiology , hypertrophic cardiomyopathy , cardiomyopathy , coronary artery disease , transplantation , stimulation , dilated cardiomyopathy , heart failure
Progressive activation delay starting at long coupling intervals of premature stimuli has been shown to correlate with sudden cardiac death in patients with hypertrophic cardiomyopathy. The purpose of this study was to elucidate the mechanism of increased activation delay in chronically diseased myocardium.
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