Open AccessMetabolic Gene Expression in Fetal and Failing Human Heart
Author(s) -
Peter Razeghi,
Martin E. Young,
Joseph L. Alcorn,
Christine S. Moravec,
O.H. Frazier,
Heinrich Taegtmeyer
Publication year - 2001
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/hc4901.100526
Subject(s) - medicine , fetus , endocrinology , gene isoform , myh6 , gene expression , heart development , heart failure , biology , gene , myh7 , pregnancy , biochemistry , genetics , embryonic stem cell
Previous studies suggest that the failing heart reactivates fetal genes and reverts to a fetal pattern of energy substrate metabolism. We tested this hypothesis by examining metabolic gene expression profiles in the fetal, nonfailing, and failing human heart.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom