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In Vivo Myocardial Protection From Ischemia/Reperfusion Injury by the Peroxisome Proliferator–Activated Receptor-γ Agonist Rosiglitazone
Author(s) -
Tianli Yue,
Jun Chen,
Weike Bao,
Padma Kumar Narayanan,
Antoine Bril,
Wen Jiang,
Paul G. Lysko,
Juan-Li Gu,
Rogely Boyce,
Dawn Zimmerman,
Timothy K. Hart,
Robin E. Buckingham,
Eliot H. Ohlstein
Publication year - 2001
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/hc4601.099403
Subject(s) - medicine , rosiglitazone , ischemia , downregulation and upregulation , myocardial infarction , cardiology , reperfusion injury , reperfusion therapy , endocrinology , myocardial stunning , agonist , infarction , anesthesia , receptor , biochemistry , chemistry , gene
Diabetes is associated with increased risk of mortality as a consequence of acute myocardial infarction. This study determined whether rosiglitazone (ROSI) could reduce myocardial infarction after ischemia/reperfusion injury.

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