Heart Rate–Independent Vagal Effect on End-Systolic Elastance of the Canine Left Ventricle Under Various Levels of Sympathetic Tone | Zendy

Yasunori Nakayama | Zendy; Hiroshi Miyano | Zendy; Toshiaki Shishido | Zendy; Masashi Inagaki | Zendy; Toru Kawada | Zendy; Masaru Sugimachi | Zendy; Kenji Sunagawa | Zendy

Open Access

Heart Rate–Independent Vagal Effect on End-Systolic Elastance of the Canine Left Ventricle Under Various Levels of Sympathetic Tone

Author(s) -

Yasunori Nakayama,

Hiroshi Miyano,

Toshiaki Shishido,

Masashi Inagaki,

Toru Kawada,

Masaru Sugimachi,

Kenji Sunagawa

Publication year - 2001

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/hc4401.099448

Subject(s) - medicine , stimulation , inotrope , heart rate , vagus nerve , vagal tone , ventricle , autonomic nervous system , cardiology , concomitant , anesthesia , blood pressure

Although we have shown that in rabbits the direct (heart rate [HR]-independent) vagal effect on left ventricular end-systolic elastance (E(es)) was negligible under minimal sympathetic tone, how underlying sympathetic tone modulates the inotropic response to vagal stimulation remains unknown.

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