Muscle Ergoreceptor Overactivity Reflects Deterioration in Clinical Status and Cardiorespiratory Reflex Control in Chronic Heart Failure
Author(s) -
Piotr Ponikowski,
Tuan Peng Chua,
Dárrel P. Francis,
Alessandro Capucci,
Andrew J.S. Coats,
Massimo Piepoli
Publication year - 2001
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/hc4401.098491
Subject(s) - medicine , baroreflex , heart failure , heart rate , hyperventilation , cardiorespiratory fitness , cardiology , hemodynamics , peripheral , ejection fraction , reflex , heart rate variability , blood pressure , anesthesia
In chronic heart failure (CHF), overactivation of ergoreceptors (afferents sensitive to the metabolic effects of muscular work) may be a link between peripheral changes, sympathetic overactivation, and increased hemodynamic and ventilatory responses to exercise. The relationship between ergoreceptors, autonomic changes, and the progression of the syndrome has not yet been studied.
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