Sympathetic Neural Mechanisms in Normal and Hypertensive Pregnancy in Humans | Zendy

John P. Greenwood | Zendy; Eleanor Scott | Zendy; J. B. Stoker | Zendy; James J. Walker | Zendy; David Mary | Zendy

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Sympathetic Neural Mechanisms in Normal and Hypertensive Pregnancy in Humans

Author(s) -

John P. Greenwood,

Eleanor Scott,

J. B. Stoker,

James J. Walker,

David Mary

Publication year - 2001

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/hc4301.098253

Subject(s) - medicine , baroreceptor , blood pressure , pregnancy , baroreflex , preeclampsia , reflex , sympathetic nervous system , sympathetic activity , heart rate , peripheral , cardiology , endocrinology , biology , genetics

Direct recordings from peripheral sympathetic nerves have shown an increased sympathetic drive in pregnancy-induced hypertension (PIH) and preeclampsia (PE). It is unknown whether sympathetic drive is altered in normal pregnancy, when arterial blood pressure can be normal or relatively low. The aim of this study was to measure and compare peripheral sympathetic discharge, its vasoconstrictor effect and its baroreceptor control, during pregnancy and postpartum in women with normal pregnancy (NP) and PIH and in normotensive nonpregnant (NN) women.

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